α-氰基丙烯酸正丁酯在选择性肝动脉栓塞中的应用.pdf

中国医学影像学杂志 Chinese Journal of Medical Imaging
269
介入医学 Interventional Medicine
Doi:10.3969/j.issn.1005-5185.2010.03.016
论著
Original Article
o-氯基丙烯酸正丁酯在选择性肝动脉栓塞中的应用
The Usage of NBCA in Transcatheter Selective Hepatic Arterial
段峰Duan,Feng
Embolization
王茂强Wang, Maoqiang
刘凤永Lu, Fengyong
王志军Wang, Zhijun
宋鹏Song,Peng
摘要】目的:评价应用@-氯基丙烯酸正丁酯(N- butyl2 cyanoacrylate,NBCA)选择
性栓塞肝动脉的安全性和有效性。材料和方法:2008-09~2009-12解放军总医院就
诊的20例患者,包括外科术后出血2例、原发性肝癌合并肝动静脉瘘形成11例、多
作者单位
囊肝7例,男性13例,女性7例;年龄45-65岁,应用NBCA进行选择性肝动脉栓塞。
100853北京
中国人民解放军总医院介入放射科
结果:所有选择性栓塞均成功,无严重并发症。2例外科术后出血患者在栓塞结東后
出血即停止,分别随访6个月、8个月,均未再发生出血。11例原发性肝癌合并肝动
静脉瘘患者中9例患者瘘口闭合,2例患者瘘口明显缩小。7例多囊肝患者栓塞区囊
通讯作者:
胂范围均不同程度缩小。结论:应用NBCA进行选择性肝动脉栓塞的近期疗效是安
王茂强
全、可靠的,但其栓塞的远期效果仍有待进一步观察。
Author Affiliations
Department of Interventional Radiology,
【关键词】a-氧基丙烯酸正丁酯;肝动脉;栓塞治疗性,放射摄影术,介入性
Chinese PLA General Hospital, Beiiing [Abstract] Objective To elevate the efficacy and
100853
nd safety of the usage of NBCA in tra
nacatheter selective hepatic arterial embolization. Materials and Methods From Sep
2008 to Dec 2009, 20 patients(13 male and 7 female, age ranged from 45 to 65 )inclu
Corresponding Author
ding 2 cases of hemorrhage after surgery, 11 cases of hepatocellular carcinoma com
Wang Maoqiang
E-mail:wangma@vip.sina.com
bined of hepatic arterial-portal vein shunt, and 7 cases of polycystic liver dis
ease NBCA was used to the hepatic arteries embolization. Results Technical success
中国图书资料分类法分类号
of interventional treatment was achieved in all 20 cases with no severe complica
R657、3
tions. The bleeding ceased immediately after interventional treatment of the 2 hemor
rhage cases and no recurrence bleding in the follow up of 6 and 8 months. 9 fistulas
收稿日期:2010-01-12
were successfully embolized and 2 fistulas were partially embolizad in 11 cases of hepa-
修回日期:2010-03-14
tocellular carcinoma combined with hepatic arterial-portal vein shunt. The cyst volume
was decreased in 7 cases of polycystie liver disease. Conclusion The short-term effica
中国医学影像学杂志
cy of transcatheter selective hepatic arterial embolization with NBCA was safe but need
2010年第18卷第3期
Chinese Journal of Medical Imaging 2010
follow-up to verify long term efficacy.
Vol.18,No.3:269-271
[ Key words) a-n-butyl-2-cyanoacrylate; hepatic artery; embolization, therapeutic; ra
diography, interventiona
的治疔方法,在治疗原发性肝癌,肝脏破裂出血、肝胜1对象和方法
血管畸形等方面已取得了良好的疗效,常用的栓塞剂1.1临床资料2008-09~2009-12解放军总医院介
包括超液化碘油、明胶海绵、聚乙烯醇微球(PVA颗入放射科应用NBCA进行选择性肝动脉栓塞的20例
粒)、弹簧圈等い2。近年来,a氯基丙烯酸正丁酯(N患者,男性13例,女性7例;年龄45-65岁,外科术后
butyl2- cyanoacrylate,NBCA)亦被作为栓塞剂进行出血2例、原发性肝癌合并肝动脉门静脉瘘形成11
选择性肝动脉栓塞,但国内外尚未见较大病例报例、多囊肝7例。遵循我国医疗法规和我院医疗伦理
道。笔者总结解放军总医院2008-09~2009-12规定,向所有患者及家属说明行介入治疗的意义、过
20例应用NBCA经导管选择性栓塞肝动脉患者的临程、治疗方式、可能产生的并发症等情况,术前患者签
床资料,旨在评价应用NBCA经导管选择性栓塞肝动署知情同意书。
脉的安全性和疗效。
1,2介入诊疗方法