三种食用油及三油酸甘油酯对小鼠血脂水平的影响.pdf

油脂加工
粮油食品科技第23卷2015年第3期
三种食用油及三油酸甘油酯
对小鼠血脂水平的影响
曾臣红,郭丽娜,刘焱,高建平
上海中医药大学中药学院,上海201203
摘要:分别用含猪油、花生油、橄榄油或三油酸甘油酯的高胆固醇乳剂或单用高剂量食用油给小
鼠灌服,比较各油脂对血脂的影响。结果表明,灌服含各食用油或三油酸甘油酯的高胆固醇乳剂
后,小鼠血清总胆固醇(TC)、肝脏指数明显升高,血清总甘油三酯(TG)含量降低。单独灌服食用
油后,三种油均引起小鼠TC水平升高;三种油和三油酸甘油均引起血清高密度脂蛋白胆固醇
HDI.-C)和低豁度指蛋白胆固醇(I.DI.-C)水平升高,体重増加;除花生油外,其他油脂均升高月
脏指数。猪油、花生油和橄榄油与胆固醇合用均引起血中总胆固醇的升高;高油摄入并未引起高甘
油三酯血症;花生油不易使脂质在肝脏积聚;三油酸甘油酯单独使用升高TC作用不明显,和胆固
醇合用后其对血中总胆固醇的升高未见有改善作用。
关键词∷猪油;花生油;橄榄油;高血脂;单不饱和脂肪酸甘油酯
中图分类号:S879.6文献标识码:A文章编号:1007-7561(2015)03-0036-(04
OI:10.16210]cki.1007-7561.2015.03.008
Effects of three kinds of edible oil and triolein on blood lipids of mice
ZENG Chen-hong, GUO Li-na, LIU Yan, GAO Jian-ping
( College of Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203
Abstract: The effects of lipin on blood lipid were compared by gavaging mice with lard, peanut oi, olive
oil or the triolein with high cholesterol emulsions or high dose of one of the edible oils, respectively
Results showed that the serum total cholesterol (TC and liver index increased significantly, and the
level of total triglyceride ( TG)in serum decreased, after the mice were gavaged with one of the three
edible oils or the triolein with high cholesterol emulsions. After being gavaged with one of the three oils,
TC of the mice was increased by each of the oils. The serum levels of high density lipoprotein cholester
ol (HDL, -C), low density lipoprotein cholesterol (T Dl -C)and body weight were all increased be-
cause of the three oils or triolein. Meanwhile, olive oil, lard and triolein increased the liver index. In
conclusion, lard, peanut oil, or olive oil mixed with cholesterol can increase serum total cholesterol lev
el; however there was no evidence showing that high dose of oils caused hypertriglyceridemia; peanut
oil was most not likely to cause fat accumulation in the liver; triolein has no obvious influence on i
creasing T(, and no significant improving effect on the rise of total cholesterol level caused by choles
terol mixed with olls
Key words: lard; peanut oil; olive oil; hyperlipidemia; monounsaturated fatty acid glyceride
随着经济的发展和人们生活方式的改变,心脑示,2002年我国居民血脂异常患病率达18.6%,患
血管疾病已成为严重危害人们健康的疾病。多数研病人数高达1.6亿圓。预防和控制血脂异常的发生
究者认为血脂异常是引起心脑血管疾病的主要因发展是防治心脑血管的关键。
素。我困第四次居民营养与健康现状调杏显
猪油、橄欖油和花生油是人们争议比较大的
种食用油。其中橄榄油倍受推昦,有研究证明橄榄
收稿日期:2014-12-03
基金项目:上海中医药大学第五期大学生创新活动项目(201210
油和花生油能够降低血液胆固醇含量,减少其在血
68049)
管上的沉积,具有防心脑血管疾病的作用。通
作者简介:曾臣红,1991年出生,女,州石阡县人,在读硕上生
通讯作者:高建平,1970年出生,女,山东蓬菜市人,博士,副教授
常认为降低血脂的作用与这两种油里富含単不饱和
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