乳果糖在老年患者结肠镜特殊治疗术前肠道准备中的应用效果研究.pdf

2013年3月16第38
短篇论著
乳果糖在老年患者结肠镜特殊治疗术前肠道准备中的
应用效果研究
白璐,白芮萌
【摘要】目的观察乳果糖在老年患者结肠镜特殊治疗术前肠道淮备中的应用效果。方法选取2008年9月
2012年7月就诊于我院的需行结肠镜特殊治疗术的老年恵者420例,采用随机数字表法将患者分为硫酸组140例,
乳果糖组140例,乳果糖艹硫酸镁组140例。硫酸镁组于术前6h口服50%硫酸镁50ml,服药后10min内饮温开水
500ml,排便后1h内再快温开水2000~2500ml,直至排出透明水样便;乳果糖銀术前3-4d依排便情况给予乳果糖
10-30mlロ服,3次/d,术前6h乳果糖200~300mlロ服,饮温开水2000~3000ml;乳果糖+硫酸镊組术前3~4d
依排便情況給予乳果糖10-30mlロ服、3次/d,术前6h口服50%硫酸镁50ml。观察3銀肠道准备满意率、患者耐
受率、不良反应及并发症发生率。结果硫酸镁组肠道淮备满意率为70.7%(99/140),乳果糖組为93.6%(131
140),乳果糖+酸镁组为90.0%(126140),嵳异有统计学意义(x2=32.8,P=0.000硫酸镁组患者耐受率为
67.9%(95/140),乳果糖组为96.4%(135/140),乳果糖+硫酸镁组为75.7%(106/140),差异有筑计学意义(x
=38.1,P=0.000)3組不良反应及并发症发生率比较,差异有統计学意义(x2=19.9,P=0.000)。结论乳果糖
应用于老年患者结肠镜特殊治疗术前肠道准备安全有效,患者耐受性好,易于接受,是一种較好的肠道准备方法。
关键词」乳果糖;硫酸镁;老年人;肠镜检查
【中图分类号」R443.7【文献标识码」Adoi:10.3969/iisn.1007-9572.2013.03.064
白璐,白芮萌,乳果糖在老年患者结肠镜特殊治疗术前肠道淮备中的应用效果研究[J].中国全科医学,2013
16(3):927-929.[www.chinagp.netJ
Application of Lactulose in Pre-operative Bowel Preparation in Elderly Patients Undergoing Special Colonoscopy Treat-
ment BA, BA Ru -meng. epartmen fgstroenteroog, the rd A d Hospital f Loning Medical College
Jinzhou 121000, China
I Abstract Ohjective To ohserve the application of lactulose in pre-operative bowel preparation in elderly patients
undergoing special colonoscopy treatment. Methods A total of 420 elderly patients admitted to our hospital between September
2008 and July 2012 needing speeial colonoscopy treatment were divided randomly into groups A, B, C, 140 in eaeh. Group A
were given oral 50% magnesium sulfate (50 ml )6 h before operation, drank warm water (500 ml 10 min after drug adminis-
tration, and more warm water(2000 -2 500 ml I h after defecation, until discharging transparent watery stools. Group B
were given. aceording to defecation, oral lactulose(10-30 ml, 3 times per day )3 4 d before operation, oral lactulose
(200-300 ml ) and warm water(2 000-3000 ml )6 h before operation. Group were given, according to defecation. ora
lactulose(10-30 ml, 3 times per day)3-4 d before operation, and then oral magnesium sulfate(50 ml)6 h before opera
tion. The satisfaction rate of bowel preparation, patients tolerance rate, incidence of adverse reactions and complications were
observed. Results The satisfaction rate of bowel preparation was 70.7%(99/140)in group A, 93.6%(131/140 )in group
B, 90. 0%(126/140)n group C, the difference was significant(x'=32.8, P=0.000). The tolerane rate was 67.9
(95/140),96.4%(135/140),75.7%(106/140), respectively, the difference was significant(x=38.1,P=0.000)
The incidence of adverse reactions and complications was significantly different(x'=19. 9, P=0.000).Conclusion Lactu
lose in preoperative preparation in elderly patients undergoing special colonoscopy treatment, safe, effective, well-tolerated
and easy to be accepted, is a good method for bowel preparation.
Key words Lactulose; Magnesium sulfate; Aged; Colonoscopy
结肠镜特殊治疔术前充分的肠道准备出血等严重并发症1。老年患者因肠道
作者单位:121000辽宁省锦州市,辽宁医
是结肠镜检査得以顺利进行的重要保证,蠕动变弱,多存在便秘等情况,术前肠道
若肠道准备不充分,肠腔内的粪便可掩盖准备较差,进行安全、有效的术前肠道准
一