氟氯氰菊酯对草鱼的急性毒性及转氨酶活性的影响.pdf

2017,36(12):2388-2393
农业环境科学学报
2017年12月
Journal of Agro-environment Science
士伟,柴背,孙輸凸,等.氟氯氧菊脂对草伯的急性毒性及转氨梅活性的影J农业环境科学学报,2017,36(12):2388-2393
WANG Wei, HAI Jing, SUN Han-chang, et al. Acute toxicity of cyfluthin and its effect on transaminase activity in grass ca(nh don idellus)J I
Journal of Agro-environment Science, 2017, 36(12): 2388-239
氟氯氰菊酯对草鱼的急性毒性及转氨酶活性的影响
王伟,柴菁2,孙翰昌3,丁诗华
(1.西南大学动物科技学院,水心科学重庆市市级重点实验室,重庆400715;2.遂j市品质量监督檢验所,W叫川遂j6290003.重庆
文理学院林学与生命科学学院,重庆402160
摘要:为了揭示鲺氯气菊?水生动物的赤性效应,本研究采用静水暴露法分析不同浓度氟氯菊(0、0.2、0.4,0.6、0.8pg·T
对草仙肝肾谷丙转氨海( A lanine aminotransferase,AIT)、谷草转氨海( A spartate aminotransferase,AST)活性的影响。研究结果示,
氯菊对草仙96 h I. Csn为1.12g·T.。在暴露初始阶段,氯菊对AIT、AST活性只有诱导作用,浓度越啬诱导作用越显
著。其中0.8g?L氯氰菊脂处理1d斤,肝脏、肾脏ALI活性分別上:?28.12%、26.74%,AST活性分別上升31.45%、22.56%;似
随着暴露时间延长,氟氯氰菊听对肝肾ALT、AST活性表现出抑制作川,且高浓度(0.8pg-L-)氟氯氰菊喘的抑制作用极显考,暴露
0d后肝肾ALT、AST活性有显著下降。与肾班相比,氟氯氰菊处理后肝朋脏ALT、AST活性变化明显。本研究结果表明,致死浓
度的氟氯氰菊可引起肝肾ALT、AST活性变化,提示氟氯氰菊污染物可影响草鱼肝肾的生理功能,对肝肾其有一定的毒性效应
关键词:草鱼;氟氯氰菊哘;谷内转酶;谷草转酶
中图分类号:X503.225文献标志码:A文章编号:1672-2043(2017)12-2388-06di:10.11654/iaes.2017-(0817
Acute toxicity of cyfluthrin and its effet on transaminase activity in grass carp(Ctenopharyngodon idellus
WANG Wei CHAL Jing. SUN Han-chang DING Shi-hua
(1. Key Laboratory of Aquatie Science of Chongqing, College of Animal Seienee and Technology, Southwest University, Chongqing 400715
China; 2. Suining Institute Product Quality Supervision& Inspection, Suining 629000 China 3. College of Forestry and Life Science.
Chongging University of Arts and Sciences, Chongqing 402160, China)
Abstract: Cyfluthrin is a widely used pesticide in agriculture, but its potential toxicity to aquatic animals is not well understood. In this
study, the effects of different concentrations of cyfluthrin (0.20 40.6 .8g L )on the activities of alanine amino rans erase( ALT)
and aspartate aminotransferase(AST )in the liver and kidney of grass carp(Ctenopharyngodon idellus ) were studied. The results showed that
the 96 h I. o(median lethal concentration ) of cyfluthrin was 1. 1 12 u. I, In the early exposure stage, cyfluthrin induced the activities of
AL T and AST and there was a positive correlation between cyfluthrin concentration and induction effects. After I day of exposure to 0.8 H
I. cyfluthrin, the AI T activity in the liver and kidney increased by 28.12% and 26.74, respectively, and the AST activity increased by
31.45and 22. 56%, respectively. However the activities of AST and A T were inhibited as exposue time inreased, and the inhibitory ef-
fects increased with cyfluthrin concentration. The activities of Al. T' and ASTIN the liver and kidney were significantly decreased after 10
days of exposure to ..L luthrin. ollowin flut hrin exposure, changes in ALT and AST activities in the liver were more obvious
than those in the kidney These results showed that sublethal concentrations of cyfluthrin induced changes n ALT and AST activities in the
liver and kidney, suggesting that cyfluthrin contaminants affeet the physiological function and have toxic effects on the liver and kidney of
grass car?
Keywords: Ctenopharyngodon idellus: cyfluthrin; ALT; AST
收稿日期:2017-06-09录用日期:2017-08-23
作者简介:.伟(1991-),男,河南郸城人,倾士研究生,主要研究方向为水产毒用学。E-mail:290265776@qq.cou
通信作者:丁诗华E-mail:1031288162cqq.com
基金项目:重庆市科委社会事业与民生保障科技创新项日(cstc2015 shms%x800