FCCV标准-Sodium Sulfite亚硫酸钠.pdf

IECC V
Monographs/Sodium Sulfite /437
Sample Soluion Trans fer aboul 200 mg of sample, accu- of waler of crystallization. The decahydrate is efllorescenl IL
rately weighed, into a glass-stoppered, 10-ML volumetric is freely soluble in water and practically insoluble in alcohol
flask dilute to volume with a solution of 10 acetic acid in A 1: 20 aqueous solution is neutral or slightly alkaline to
chloroform; and mix. If necessary, heat the mixture carefully litmus paper
to dissolve the sample and then cool before diluting to volume
with the solvent mixture
Function Agent in caramel production
Standard Solution A Transfer about 10 mg of USP Sodium
Stearyl Maleate Reference Standard, accurately weighed, into
a 100-ml volumetric [ask dilute to volume with 10% acetic
REOUIREMENTS
acid in chloroform, and shake well
Standard Soltion B Transfer about 20 mg of stearyl alco
Labeling Indicate whether it is anhydrous or the decay-
hol(Aldrich, or equivalent), accurately weighed, into a 100-
dr
ML volumetric flask. dilute to volume with 10%o acetic acid
Identification A 1: 20 aqueous solution gives positive tests
in chloroform. and shake well
for Sodiam and for Sulfate, Aj
ppendix IIIA
tandard Solution C Mix 25.0 ML of Standard Solution
Assay Not less than 99. 0% and not more than 100.5% of
A with 25.0 ML of Standard Solution B and shake well. This
Na2 SO4 aller drying
mixture represents 0.25% of sodium stearyl maleate and 0.5%% Lead
lot more than 2 mg/kg
of stearyl alcohol, based upon the weight (200 mg)of the
Loss on Drying Anhydrous: Not more than 10: Becah
sample taken
drate: Between 51. 0% and 57.0%
Procedure Spol 10 WL each of the Sample Solation and
Selenium Not more than 0.0030
of Standard Solution C at the bottom of the plate. Allow the
spots to dry, then place the plate in a suitable chromatographic TESTS
chamber containing a 5: 5: 1(/v )mixture of toluene, hexane
glacial acetic
eviously equ
ated. a
p
Assay Dissolve about 500 mg of sample, previously dried
oy ascending chromatography [or 30 min to effect one pass. at 105 for 4 h and accurately weighed, in 200 ml of water,
Remove the plate from the tank, dry in the air for 10 min, add I ml of hydrochloric acid, and heat to boiling. Gradually
and then heat in an oven at 90 for 2 min. After cooling to add, in small portions and while constantly stirring, an excess
room temperature, replace the plate in the chamber for a of hot barium chloride TS(about 10 ml), and heat the mixture
second pass of 30 min. After the second pass, remove the on a steam bath for I h. Collect the precipitate on a retentive,
plate from the chamber and dry in the air for 15 to 20 min. ashless lilter paper, wash until free from chloride, and place
Spray evenly with a mixture consisting of.5% of potassium the filter into a suitable tared crucible. Carefully burn away
permanganate and 0.3% of sodium carbonate in water. Maleate the paper, and ignite at 800+ to constant weight. The
and Fumarate appear as yellow spots against a pink back-weighl of the barium sulfate so oblained, multiplied by 0.6086
ground Spray with sulfuric acid and heat in an oven at 150 indicates its equivalent of Na?SO
detect the stear
Lead Determine as directed in the AP/C *xtracti0m Met