芬吗通联合坤泰胶囊在体外受精-胚胎移植卵巢低反应患者中的应用.pdf

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实用医学杂志2014年第30卷第14期
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(收稿:2013-12-24编辑:陈兵)
芬吗通联合坤泰胶囊在体外受精一胚胎移植卵巢
低反应患者中的应用
李巍安丽红张歌王兴玲孙丽君管一春娄华袁思武
摘要目的:探讨芬吗通联合坤泰胶在体外受精一胚胎移植(IVF-ET)卵果低反应(POR)患者中的应用。
方法:选取在郑州大学第三附属医院生殖医学科行IVF中的POR患者,随机筛选120例,进入第二周期助孕
前,行芬吗通联合妽泰胶曩预处理3个月经周期,行自身对照,比較卵泡刺激素(FSH)、促黄体生成素(LH)、雌
二醇(E2)、抗苗勒管激素(AMH)、窦卵泡数、动脉收缩期峰值流逑(PSW)、促性腺激亲(Cn)用量及天数、HCC日
E2值、获卵数、受勅率、优质胚胎数、周期取消率的差异。结果:经预处理,患者的FSH、LH水平降低,AMH、PSV
水平增加、HCG日E2值、窦卵泡数、获印数、受精率、优质胚胎数均增加,周期取消率降低,差异具有统计学意
义(P<0.05)。结论:芬吗通联合坤泰胶淾的治疗可提高POR患者卵巢储备功能,改善ⅣVF结局。
关键词卿樂低反应;IVF;芬吗通;坤泰胶;微刺激
Application of femoston combined with Kunta capsule in poor ovarian responders receiving vitro
fertilization LI Wei-wei, AN Li-hong, ZHANG Ge, WA NG Xing-ling, SUN Li-jun, GUA W Yi-chun, LOU Hua
YA E-w Rowton ee the h o ow Wenzhou 4502, in
Abstract Objective To investigate application of femoston combined with Kuntai capsule in poor ovarian
responders(PORS )receiving vir fertilization. Methods 10 women with poor ovarian response after receiving IV
were s randomly elected. Pre-treatment with femoston plus Kuntai capsule was used for three menstrual cyeles before
the next cycle of assisted reproductive reatment. FSH, LH, Ez, AMH, number of antral follicles, PSV, days of Gn
ampoules
Gn, cycle cancellation rate, Ez value of the day of FCG, follicle of less than 16mm, number of oocytes
fertilization rate, and number of good quality embryos were compared before and after treatment used. Results After
pre-treatment, levels of FSH and I H were decreased, AMH, PSV were increased, E, value of
day of HCG
number of antral follicles, follicle of less than 16 mm, oocytes, fertilization rate, and good quality embryos were
increased; cycle cancellation rate was decreased, with significant differences(P <0.05) Conclusions Femoston
combined with kuntai capsule can effectively increase the functional reserve of the ovarian in poor ovarian responders
and can improve the outcome of IVF.
Key words) POR; IVF; Femoston; Kuntai capsule; Microstimulation
卵巢储备功能下降可引起卵巢产生卵子的能力减弱,卵子数量及质量下降,导致生育能力减弱。它
是导致卵巢低反应( poor ovarian responders,POR)
doi:10.3969/jisn.1006-5725,2014.14.045
的重要原因之一。在进行体外受精一胚胎移植(in
作者单位:450052河南省郑州大学第三附属医院生殖医学科
vitro fertilization- embryo transfer,TVF-ET)过程中,
通